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Interestingly, all authors have reported that venular perfusion is always preserved, whatever the severity of alteration in smaller vessels [ 3, 8].
The prognostic capacity of HRV analysis in sepsis has been evaluated by correlating standardized measures of illness severity with severity of alteration in HRV, and by demonstrating poor outcome or high mortality in subgroups of patients who demonstrate significantly altered HRV.
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Ninety-four of the 129 rams classified as unsuitable for breeding were recommended for culling, owing to the severity of alterations.
The severity of the alteration was in direct relationship to the induction period of arthritis similar to the results reported by (35, 8, and 10).
However, severe microcephaly and the spectrum and severity of clinical alterations distinguished this case from eight other cases and hampered, but did not exclude, the diagnosis of autism.
Nevertheless, these parameters provide only limited information about the nature and severity of tissue alterations in the central nervous system.
The amino acid position and the severity of the alterations in chemical properties of the mutated protein might govern the observed/resulting phenotypic effect.
However, the nature and severity of histopathological alterations in vivo can be quite different depending on the species and virulence of the rotavirus strain.
After each clinical examination and the serological results for B. ovis, rams were classified as suitable or unsuitable breeders, according to the severity of the alterations recorded.
Rather, the presence of the NTAP appears to reduce the severity of the alterations, either by reducing the stability or activity of the protein, possibly by affecting its interaction with other proteins.
In type 2 diabetic patients, increased collagen type IV urine excretion was associated with the severity of morphological alterations in fibrosis, albeit no direct relationship with the content of collagen type IV in the kidney could be observed [ 56].
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