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We suggest that the BTAT could be used to assess the incidence of tongue-tie in newborn infants as well as objectively assessing severity in research studies investigating the impact of frenotomy.
The debate regarding use of diagnostic categories versus symptom severity in research and clinical practice is ongoing [ 75, 76] and studies that include the capacity to measure both will add valuable information to assist researchers and clinicians as we develop future classificatory systems and clinical guidelines.
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It is used routinely as a screening tool in clinical practice and as a standard depression severity outcome in research.
This evidence provides support for the validity of the use of OKS when used across the spectrum of knee OA disease severity, both in research and clinical practice.
Moreover, PASI is the most widely used measure of severity in the research as well as the clinical setting.
Second, we defined TBI severity using GCS, which is the most commonly used score for classification of severity in TBI research.
Further studies are clearly indicated to define and improve validated, sensitive methods for evaluating pain severity in all research animal species.
Two of the most commonly implemented self-completed measures of pain severity in clinical research are the McGill Pain Questionnaire Short-Form (MPQ-SF) [ 19, 20] and The Brief Pain Inventory Short-Form (BPI-SF) [ 21].
Though depressive symptoms were not validated by a psychiatrist in our study, we used the SCL-CD6 scale found earlier to be psychometrically valid for measuring depression severity in epidemiological research; its predictive validity has also been confirmed in relation to subsequent hospitalisations for depressive episodes and purchases of antidepressants [ 31].
The PSQI is now one of the most commonly used assessments for the evaluation of insomnia severity in sleep research [ 65, 66], and its validity has been demonstrated for patients with mental disorders [ 62, 67], for patients with different somatic diseases [ 68], and for healthy elderly subjects [ 63].
The PHQ-15 is a brief, self-administered questionnaire that has proved useful in screening for somatization and in monitoring somatic symptom severity in clinical practice and in research.
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