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Red arrowheads: severing in half helices in cofilin clusters; blue arrowheads: severing in a bare half helix immediately neighboring a cofilin cluster; white arrowheads: cofilin clusters.
Was there a need for the camera to hover on the severing, in terms of the development of the theme of separation?
Furthermore, the inhibitory effect of localized glutamylation propagates across neighboring microtubules, modulating severing in trans.
Red, blue, and green arrowheads indicate severing in half helices in cofilin clusters, in a bare half helix immediately neighboring a cofilin cluster, and in bare zones more than half a helix away from cofilin clusters, respectively.
Altogether, the data suggest that the differences in the ability of SPR2 to prevent severing in different cell types are correlated with large differences in SPR2 dynamics in the two cell types.
DOI: http://dx.doi.org/10.7554/eLife.04806.022 10.7554/eLiFigure06 figuregure 6—figure supplement 4. Representative still images from Video 12, showing severing in actin filaments decorated with high concentrations of cofilin.
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Its location south of Gaza City enables Israel to slice the strip in two, severing Palestinians in places like Rafah from their main hospitals, universities and businesses in Gaza City.
Severing communication in medias res ("in the middle of things" in Latin), and/or inhibiting communication between tumors cells by suppressing TnT formation in the first place, may be potential goals of new or existing targeted cancer therapies.
Point mutations in N-Srv2 that abolish the enhanced severing activity in vitro also cause striking defects in actin organization in vivo.
Red arrowheads: severing points in end half helices in cofilin clusters; white arrowheads: cofilin-rod clusters.
The developers of an East Side condo tower conceived as one of the country's first "spa living" residences said Wednesday that they were forming a partnership with a new spa operator, American Leisure, after severing ties in October with Miraval, the resort based in Tucson.
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