Sentence examples for severely toxic from inspiring English sources

But there's no strong evidence for severely toxic effects in humans from inhaling or touching mold, according to the Centers for Disease Control and Prevention.

Many anticholinesterases, when administered in large doses, are severely toxic, achieving their effects by causing a continual stimulation of the parasympathetic nervous system.

Expressed in thickly impastoed, concentric circle charts partly filled with graded colors, they bear titles like "Mild and Moderately Toxic," "Mildly, Moderately and Severely Toxic," etc. Their echoes of unorthodox "system" painters like Al Jensen are apparent.

Users knew what they were buying – unlike the dozens of people who have died in the UK in recent years when they took Ecstasy pills that contained the severely toxic drug PMA.

In addition, it has recently been demonstrated that short fibre lengths less than 5 µm are not severely toxic and that only long and rigid CNTs have an asbestos-like effects [103].

And because he looks, plays, and giggles like every other 4-year-old, it can be hard to keep top of mind that he faces a serious danger on a constant basis because the thing that is so severely toxic to him, is completely edible to everyone else.

Our review found that selecting a FIH dose that is 1/6th the highest non-severely toxic dose (HNSTD) in cynomolgus monkeys or 1/10th the STD10 in rodents scaled according to body surface area (BSA) generally resulted in the acceptable balance of safety and efficient dose-escalation in a Phase 1 trial.

We concluded that approaches based on receptor occupancy, highest non-severely toxic dose, or no-observed adverse effect level are not acceptable for selecting the FIH dose as they resulted in doses close to or above the MTDs, HHDs, or the RHD.

To study the effect of ganetespib on survival, beginning one day after tumor cell implantation, the drug was dosed intravenously at its highest non-severely toxic dose (HNSTD) of 25 mg/kg on a 5×/week schedule through day 19.

The starting dose (7 mg/m) was selected based on a conservative estimate using the highest non-severely toxic dose established in a once-weekly, 4-week repeat dose study in cynomolgus monkeys.

Risk factor two is the hetero-oligomer formation of the Aβ K16N peptide with its WT counterpart which severely increases toxicity, especially of the usually non-toxic oligomers.