Exact(8)
This means that the picture they create is frequently inaccurate, and often leads to severely problematic unintended consequences (pdf).
"I certainly sympathize with physicians about increasing medical malpractice costs, but imposing a surcharge may be severely problematic, especially from a legal standpoint," Mr. Blumenthal said.
This is a problem because it is not at all evident how epistemic justification should be understood, and classical accounts of that notion have turned out to be severely problematic.
Having failed to stop Attorney General Ashcroft from implementing severely problematic revisions in 2003, members of Congress repeatedly objected when Attorney General Mukasey did so again in late 2008.
Determining DIF is valuable as detection of any severely problematic items (those presenting with significant DIF) would be expected even in small samples.
At each time point, the difficulty performing each of the 3 activities was scored on a 0-4 scale: 0 = No Problem, 1 = Mildly Problematic, 2 = Moderately Problematic, 3 = Severely Problematic, and 4 = Impossible.
This loss is severely problematic for topology-based analytical methods, in that it effectively disconnects reactions, arbitrarily and randomly linearizes otherwise complex interconnected relationships and eliminates potentially significant crosstalk between pathways, largely by disconnecting the functions of multifunction proteins.
While not as severely problematic as hurricanes or winter storms, thunderstorms, flooding, monsoons, etc. all plague different regions of the world throughout the year, some more frequently or regularly than others.
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Justyna Jupowicz-Kozak
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