Sentence examples for severely induced from inspiring English sources

Unfortunately, the atRA-loaded microspheres severely induced inflammatory responses: that is, atRA released from the microspheres significantly induced the proliferation of fibroblasts and collagen deposition, thereby causing a permeability barrier for drugs from entering the blood stream.

Interestingly, TA injections severely induced macrophage activation (Fig.  3).

The study was further extended to explore the suppression of withdrawal signs by D. denudatum in rats during severely induced morphine dependence.

Among them, BCL2/adenovirus E1B interacting protein 3 (bnis3) is activated in ventricular myocytes in response to stress when mitochondria are severely damaged, inducing mitochondrial dysfunction and subsequent cell death (Regula 2002; Gustafsson 2011).

N2a cells expressing pro-aggregant TauRDΔ displayed a severely reduced KCl induced Ca++ influx (−222%) compared to non-induced control cells, even before aggregates became detectable (pro-aggregant TauRDΔ: 370.4 ± 26% of baseline, n = 16; non-induced control cells: 592.07 ± 42% of baseline, n = 38, t-test p < 0.0017; Figure  8i).

In addition, the combined loss of p73 and p53 induces genomic instability more severely than that induced by loss of p53 alone [ 6].

Despite the already high baseline T-cell apoptosis observed in the B cell-depleted culture from mildly arthritic mice, the addition of B cells from moderately and mildly arthritic mice, but not severely arthritic mice, induced a significant increase in T-cell apoptosis.

In sedentary Apc(Min/+) mice at 26 wk of age anemia was present, and markers of apoptosis were induced in severely cachectic muscle.

Proliferation of TRAF6-ΔB B cells in response to LPS, CpG-DNA and anti-CD40 Ab was severely impaired, while proliferation induced by BCR crosslinking was comparable to the control B cells.

RNAi-mediated suppression of Gr68a severely reduces neural responses induced by (R, Z, Z )-CH503 (red).

Under the same conditions, pretreatment of cells with pan-caspase inhibitor z-VAD-FMK (100  μmol/L) severely interfered with apoptosis induced by BTZ and ATO (4.09%), which was comparable to the nontreated control cell group (5.84%) (Fig. 2C).