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We classified phenotypes as either unaffected, moderately defective (vertebral segmentation defects and malformed vertebrae with minimal lateral curvature), or severely defective (lateral curvature of vertebrae usually accompanied by highly malformed vertebrae and vertebral segmentation defects).
SENP7-depleted embryos exhibited severely defective maternal-zygotic transition and progressive degeneration, resulting in nearly no blastocyst production.
Metal conductivity determines the behavior of carrier scattering in severely defective degenerate semiconductors, while the semiconductor character defines the activation processes.
Recently, Lefebvre et al., 2011 showed an Arabidopsis mutant (esk1) that decreased in cold, salt tolerance and water use efficiency was severely defective in chemical composition of xylem cell wall, altered vascular tissues and impaired water transport.
Is that what you really want? 3. Please try this brief thought experiment: Your daughter, or wife, or some other women you care about, finds herself pregnant with a severely defective fetus that will not be likely to survive in the long or even short run, and endangers her own health or even life.
In contrast, PO females mated to BW males (PO×BW) produce overgrown and severely defective offspring.
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Loss of the first bromodomain of BRDT results in improper/incomplete spermatid elongation and severely morphologically defective sperm.
However, at 4°C, all four mutants were severely growth defective, and completely failed to grow both in liquid broth and on ABM-agar plates (Fig. 2B).
We report here that recC, recB, and recCBD deleted strains of P. syrinage are all severely growth defective at 4°C, but grow almost normally at 22°C.
In Sun1 −/−Sun2 −/− mice, lamination of the cerebral neocortex is severely impaired owing to defective neuronal migration (Zhang et al., 2009).
In Cxcr2−/− mice, immunity against bacterial infection is severely compromised due to defective neutrophil chemotaxis (Tsai et al, 2000; Tateda et al, 2001).
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