Several allelic variants were reported for IYD, which severely compromise the dehalogenase activity of the enzyme leading to hypothyroidism (dyshormonogenesis 4, OMIM 612025) [70,71].
But that would severely compromise their ability to provide credit, so a more realistic approach is needed.
In the documents, Mr. Spitzer's lawyers argue that disclosing information such as that sought by the Senate would severely compromise the administration's ability to formulate public policy, with "dire consequences for the public interest".
At the same time, it will cut or severely compromise telecommunications systems, making it difficult or impossible to track one another down via phone calls, e-mails, or texts.
Missing data can severely compromise data quality and utility.
These perturbations severely compromise O2-dependent energy production.
Borehole instability will severely compromise this function and reduce the working life of the well.
However, substrate and product diffusion can severely compromise these HTS assays.
Unfortunately, complications related to cardiac and renal disease often severely compromise patient survival.
However, the continuous period in derating operation of CCS devices will severely compromise the CO2 reduction objective.
The issue of form error is critical since it may severely compromise the performance of the designed optical system.
