Sentence examples for severe underlying diseases from inspiring English sources
The detection rate of perinatal stroke is rising due to improved neuroradiological imaging techniques, increased survival of neonates with severe underlying diseases and an increased awareness of the diagnosis by pediatricians.
However, severe hematogenous infections caused by B. cereus have been reported, especially in drug addicts, premature neonates, and patients with severe underlying diseases or compromised immunity [3].
Once again, these patients had severe underlying diseases and comorbidities and all but one received at least one other potentially nephrotoxic drug.
In these latter patients, contra-indications were hemorrhagic stroke (n = 10), multiple organ failure (n = 3) and severe underlying diseases (n = 2).
Severe underlying diseases and condition such as diabetes mellitus, liver cirrhosis, and immunosuppression are implicated in the patient's prognosis, although we did not observe any significance in this study [10, 15, 22 26].
Nevertheless, severe underlying diseases limit our ability to administer optimally chemotherapy.
As in previous studies of S. aureus bacteremia, older age, use of immunosuppressants, severe underlying disease, high severity of illness, and inappropriate definitive antibiotics were independent risk factors for mortality [ 8, 20- 22].
Age and underlying disease were strongly correlated: all our patients with severe underlying disease were older (age >65 years).
These studies have identified hyponatremia as an independent predictor of mortality after adjustments for potential confounders reflecting severity of underlying disease, and thus suggested that hyponatremia is not only a marker of severe underlying disease, but also a direct contributor to mortality.
Maintaining fidelity is challenged by the complex, multi-domain design of the intervention implemented across multiple sites and delivered to an older, heterogeneous participant pool with severe underlying disease and multi-morbidity.
Conclusions: Critically ill patients in whom HSV-1 from BAL is isolated, have about 40% chance of dying, mainly because of severe underlying disease and comorbidity, which may predispose to endogenous reactivation of the virus.
