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Recent findings from studies of tuberculosis infection and of patients with Mendelian predisposition to severe tuberculosis have started to reveal human loci influencing tuberculosis outcomes.
Symptoms such as vomiting, shivering, and sweating suggest severe tuberculosis.
Kornfeld arrived in Switzerland in 1949 and was nursed in Davos for four years as he recovered from severe tuberculosis.
Kornfeld arrived in Switzerland in 1949 and was nursed in Davos, Switzerland for four years as he recovered from severe tuberculosis.
He reappeared four years later in Versailles suffering from severe tuberculosis, and died shortly afterwards, following a lengthy bout of exudative diarrhoea.
It also provides additional support for the view that severe tuberculosis in childhood may result from a collection of single-gene inborn errors of immunity.
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In 1930, however, the first of several severe attacks of tuberculosis put an end to his sporting career and interrupted his studies.
P2 was diagnosed with severe pulmonary tuberculosis at seven months of age, which was bacteriologically confirmed (from gastric lavage), and treated with isoniazid and rifampin (Figure 1).
The LNTB (Less severe extrapulmonary tuberculosis) group included 24 (8%) patients with extra-pulmonary peripheral sites restricted to lymph nodes, peripheral joints, skin or pleural effusions without involvement of lung parenchyma.
Severe extrapulmonary tuberculosis (SevTB) identified in 172 (57.1%) patients included those with two or more noncontiguous sites, miliary mottling, or involvement of meningitis, pericardium, spinal, intestinal and splenic sites with or without lung involvement.
The cross sectional design of this study restricts our conclusions and does not provide information on whether poor nutritional status is a predictor of more severe pulmonary tuberculosis.
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