Sentence examples for severe toxicities from inspiring English sources

It has been known for its anticancer efficacy and lack of severe toxicities to normal tissues.

The severe toxicities of organotin(IV) pollutants have been extensively investigated over the past few decades.

However, SAHA has adverse effects such as poor pharmacokinetic properties and severe toxicities in clinical use.

Various Protein tyrosine kinase inhibitors are available but face poor bioavailability, severe toxicities and recent cases of drug-resistant cancers prompts for development of better drug molecules.

Metronomic chemotherapy, which was originally designed to inhibit angiogenesis, involves low-dose chemotherapeutic agents administered in a frequent regular schedule with no prolonged breaks and minimizes severe toxicities.

The severe toxicities for 177Lu-DOTATATE included hepatic insufficiency in 0.6%, myelodysplastic syndrome in 0.8% and renal insufficiency in 0.4% of patients in this study.

Nevertheless, factors like limited bioavailability, severe toxicities, unfavorable pharmacokinetics etc. still prove to be the major impediments in the field which warrant considerable scope for further research investigations.

"Right now, the current chemotherapy and radiation used as part of this procedure causes lasting damage, and leaves people vulnerable to severe toxicities and life-threatening infections," Czechowicz says.

Clinical administration of high doses of anticancer drugs to overcome resistance leads to severe toxicities [1].

Mostly the clinical administration of high doses of anticancer drugs to overcome resistance leads to severe toxicities [40].

In the assessment of safety, our toxicities profiles showed that the addition of nab-paclitaxel to cyclophosphamide did not bring severe toxicities to patients participating this trial.