A 12-year-old boy known to have idiopathic HES presented to our ED with a complaint of cough, shortness of breath (SOB), and severe chest tightness for the previous 1 h.
Three days after exposure, the subject had an onset of severe chest tightness, together with chills, fatigue, cough, and fever around 39°C.
He had numerous emergency visits due to severe exacerbations, in several of which he had throat tightness, inability to breath, intense stridor and syncope.
Botox did have more side effects than a placebo, including a greater incidence of muscle weakness, double vision, drooping eyelids, neck pain and muscle tightness, though no severe side effects were reported.
For adolescents, the most severe symptoms were coughing and chest tightness (mean rating = 6.9 for both), followed by fatigue, shortness of breath, and wheezing (6.7, 6.6, and 6.6, respectively).
Symptoms and signs of this allergic reaction include mild rash to diffuse erythroderma, pruritus, urticaria, angioedema, tachycardia, chest tightness, bronchospasm, dyspnea, and at the severe end, cardiopulmonary collapse.
Assigning breathlessness or chest tightness from cardiac ischemia to anxiety, and severe agitation from psychosis and threats of suicide from worsening depression to illicit drug or alcohol abuse, can result in life-threatening consequences.
Surprisingly, increased risks of severe symptoms of the airways, e.g., wheeze and/or chest tightness, which are associated with asthma (46), were recorded in the present study.
A more severe condition called vaginismus can also be responsible for vaginal tightness.
