Sentence examples for severe structural alterations from inspiring English sources
The Literature has shown that thymus can be a target for many pathogens and severe structural alterations take place in this organ during infectious diseases.
The vertebrae mineralize around these abnormal protein deposits, which may explain the severe structural alterations we observed.
Consistently, we detected severe structural alterations of protonephridial tubules in NPHP RNAi) animals, particularly of the proximal segment.
While patients with WRN mutation have to cope with an accumulation of DNA damage, LMNA mutant cells are associated to severe structural alterations in the nucleus, leading to chromatin reorganization and subsequent epigenetic alterations.
Here, we analyze the phenotype of RhoE null mice and show that RhoE is essential for a correct development since the absence of RhoE expression induces severe behavioral and structural alterations and becomes deleterious few weeks after birth.
All these observations indicate severe morphological and structural alterations occurring in the diabetic heart (19, 23).
Adult flies fed an HSD develop severe structural and functional alterations of the heart (Table 2), as well as essentially all the phenotypes observed in the larval model (Musselman et al., 2011; Na et al., 2013).
In contrast, incubation of either of the two cell lines with 500 μg/mL of the other Rhododendron leaf extracts resulted in severe structural and functional alterations often associated with signs of apoptosis.
Type 1 diabetes mellitus is characterized by severe hyperglycemia at the whole body as well as several serious functional and structural alterations in the myocardium and vasculature.
These derangements, clinically classified as alcoholic myopathy, are likely caused by severe metabolic, physiological and structural alterations to skeletal muscle (Fernandez-Sola et al., 2007; Preedy et al., 2003).
These data suggest possible functional neuroanatomical compensatory processes in cerebellar and cortical areas in a VPT cohort without severe periventricular damage, which also presents several structural brain alterations.
