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"The tightening of credit conditions along with changing expectations of house price growth and a general weakening in consumer confidence in the economy have led to a severe slowing in housing market activity," said Fionnuala Earley, the Nationwide's chief economist.
Table 2 Electroencephalographic patterns in sepsis Electroencephalographic findings Association with adverse outcome References Normal EEG 0 [76] Theta (mild generalized slowing) + [76] Delta (severe slowing) + [76] Triphasic waves + [76] Periodic epileptiform discharges + [73, 74, 77] Electrographic seizures ++ [73] Generalized suppression or burst-suppression +++ [75, 76].
2 In late infantile MLD, peripheral neuropathy often precedes the CNS manifestations of the disease and is characterized by severe slowing of motor and sensory conduction.
The presence of background slowing with dominant theta-delta activity was associated with a poor outcome, although more severe slowing was not.
Severe slowing of nerve conduction velocity is seen in patients with mutations in PRX and FGD4 and also in the myelin-associated genes MPZ, EGR and PMP22.
UT Twi mice analyzed at PND30 showed severe slowing of MCV (≈7 m/s) as compared with age-matched WT controls (≈28 m/s).
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tra1- L3733A was synthetically lethal with spt20Δ and severe slow growth was seen with ada1Δ tra1- L3733A and eaf1Δ tra1- L3733A.
Tolerance to stimulant laxatives is rare and occurs mainly in the patients with more severe slow transit constipation.
Deletion of SPT10 causes a severe slow growth phenotype, showing that Spt10 is critical for normal cell division.
Thus, proposing a colectomy to patients with severe slow transit constipation, without having evaluated the motility of both ano-rectum and small bowel by manometry, should be avoided.
This is particularly the case in the group of patients with more severe slow transit constipation and in patients with neurologic disorders such as Parkinson's disease, multiple sclerosis, and paraplegia.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com