Moreover, straight Cdk1 inhibition in mitosis induces mitotic slippage, resulting in severe cytokinesis defects (Potapova et al., 2011; Vassilev et al., 2006).
This makes it far less likely although still possible that endemic slippage is a particularly severe problem amongst now allegedly comparatively more engorged Thai teenagers.
As compared with pressure-driven flows in nonslip microchannels, pressure-driven flows in microchannels with hydrodynamic slippage are found to experience severer flow reduction (streaming potential effect).
With that in mind, the ideal antimitotic agent should therefore be effective enough to prevent mitotic slippage, or even if slippage occurs, severe CIN that compromises tumor cell viability must be invoked by the single inhibitor or in combination with other drugs.
Such slippage is not hard to explain.
For cells tested to 4.2, 4.4 or 4.5 V, the greater the fraction of testing time spent at high potential, the lower the coulombic efficiency and the greater the charge endpoint capacity slippage rate, with the effects being more severe at higher potential.
For our democracies, the slippage is a doubly dangerous one.
In addition, organisms might minimize the numbers of tracts in coding regions to avoid the severe, even fatal frame-shift mutations that might be introduced by slippage-replication events at tracts [ 3- 5, 42].
There has been slippage since.
