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Severity can be minimized by using the least severe procedures and sequence of procedures, and by setting humane endpoints, and, in a sequence of experiments, by setting review points and starting with lower severity studies.
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Animals were subjected to a staggering 1.9 million "mild" procedures, approximately 557,000 "moderate" procedures and endured at least 184,000 "severe" procedures in the past year.
That is, we may regard the products of our argument-making practices as logically strong only if we presume, at the dialectical level, that we have submitted arguments and counterarguments to sufficiently severe procedures of critical discussion as Habermas (TCA 1: 26) puts it, a "ritualized competition for the better arguments".
Meanwhile, "severe" procedures can include irradiation or chemotherapy with a lethal dose, deliberately breeding animals to have painful genetic disorders and increasingly poisoning animals with toxic substances until they die.
"Severe" procedures can include irradiation or chemotherapy with a lethal dose, deliberately breeding animals to have painful genetic disorders and increasingly poisoning animals with toxic substances until they die.
For each woman, we obtained the date of the first and last histological sample recorded in the clinic and requested the most severe procedure (that is, whether it was a punch biopsy or material from excisional treatment) carried out at these visits.
Since the typical analytical procedure requires long Soxhlet extractions and the use of large quantities of sample (30 50 g), in this work we have optimised the focused ultrasound extraction (FUSE) and the microwave-assisted extraction (MAE) to make available a less severe procedure.
In elderly patients, however, inadequate screw purchase in osteoporotic bone can result in severe procedure-related complications.
However, a selection bias resulted from a more frequent use of bridging therapy in severe procedure (most physicians anticipated the increased cardiovascular risk in patients undergoing major procedure).
No cases of endophthalmitis, retinal detachment or any other severe procedure-related complications were observed in a total of 652 injections.
This, in addition to the presence of invasive devices, surgical procedures and severe co-morbid conditions are risk factors for RGNB infection and colonization [ 22- 25].
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