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In mussels from the polluted site, severe morphological alterations were observed in gills, mainly involved in nutrient uptake and gas exchange.
In concordance, the results presented in this paper demonstrate that CD and LA provoked severe morphological alterations, among them, the most conspicuous were the shrank caudal region; therefore it suggests that actin participate in the caudal movement.
These extensions after further incubation were ruptured and cause severe morphological alterations leading to the loss in viability.
The most severe morphological alterations caused by ExoS-GAP in both cell lines were alterations in actin organization affecting leading edge or lamellipodium architecture.
We show that CAA at later disease stages is accompanied by severe morphological alterations of brain blood vessels including stenoses, BBB leakages and the loss of vascular smooth muscle cells (SMCs).
Transgenic plants expressing the miR156 gene that exhibited severe morphological alterations was used to investigate the effects of miR156 over-expression on its downstream genes using Affymetrix microarray analysis [ 82].
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This growth inhibition was associated with several morphological alterations observed in promastigote forms.
All these observations indicate severe morphological and structural alterations occurring in the diabetic heart (19, 23).
Mutants display severe physiological and morphological alterations caused by perturbed liver function.
As a result of their significant involvement in early development, changes in expression of Hox genes may cause severe morphological and/or physiological alterations, which are expected to play important roles in driving evolutionary changes.
While the expansion of isolated cells in the static environment of a culture dish is easy to perform, developing tissues frequently illustrate severe morphological, physiological and biochemical alterations caused by dedifferentiation especially in combination with innovative biomaterials[1 8].
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