Sentence examples for severe methodological limitations from inspiring English sources

In general, there were severe methodological limitations to these papers, with small numbers of patients and the lack of blinding or independent assessment of outcomes.

However, these findings must be interpreted within the severe methodological limitations of many studies, including small sample sizes, variable study entry criteria, short duration of trials, heterogeneous outcome assessment methods, and lack of detail on intervention methods.

Both systematic reviews suggest there are limited studies that demonstrate the effectiveness of aromatherapy and the majority of studies to date have been challenged by severe methodological limitations.

11 12 13 Most available studies on fibre treatment have severe methodological limitations, such as inadequate outcome assessment and lack of placebo control, and all trials were done in secondary care.

Unfortunately we calculated no inter-rater correlation, which is also a severe methodological limitation.

Our study has several methodological limitations.

The present study has several methodological limitations.

Findings should be viewed in light of several methodological limitations.

Several methodological limitations of earlier studies were identified and overcome.

The present study had several methodological limitations.

Several methodological limitations are to be discussed.