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Despite severe membrane remodeling, stage 4-cells appear to remain viable for several days, suggesting that the essential physiological functions of the cells are still intact.
Natural organic matter present in field water causes severe membrane fouling.
Frequent shutdowns of the plant were observed due to severe membrane fouling.
Filtration of pesticides from field water suffers severe membrane fouling due to the composition of field water.
However, it often suffers from the severe membrane fouling due to the nonspecific interactions between membrane surface and foulants.
The incorporation of the MCNs into the membranes introduces a different strategy of inhibiting biomolecule adsorption and bacterial attachment to the membrane surface, instead of killing the bacteria which may lead to more severe membrane fouling by the intracellular substances.
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Although the hemolytic activity test provides valuable results in the context of a safety assessment of a recombinant protein, not all harmful substances to cells cause severe cell membrane injury that culminate in disruption of the cell membrane and release of hemoglobin.
These results indicate that colanic acid, a hydrophilic extracellular polysaccharide, and possible polysaccharides with similar characteristics with colanic acid are considered as a major cause of severe irreversible membrane fouling (i.e., pore-clogging) regardless of biofilm formation (dynamic membrane).
The bench-scale cross-flow filtration tests followed by filtration resistance measurement revealed that RcsF+ caused severe irreversible membrane fouling (i.e., pore-clogging), whereas less extracellular polysaccharide-producing strains caused moderate but reversible fouling to all membranes used in this study.
Autopsy revealed necrotising enterocolitis, severe hyaline membrane disease, severe generalized lymphocytic depletion and haemosidrosis of the liver and spleen.
Severe synovial membrane inflammation (synovitis) with significant angiogenesis and influx of inflammatory leukocytes is the hallmark of RA [ 4].
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