Sentence examples similar to severe matter from inspiring English sources

Lawyers and legal authorities like the police may need to be contacted if the ethics violation was also illegal, but for less severe matters, an ethics expert might be a counselor or adviser.[3].

Our present findings equally showed that larger CTG repeat sizes were associated with more severe white matter affection in several brain regions.

All other neuropsychological parameters did not differ between patients with myotonic dystrophy types 1 and 2. Patients with myotonic dystrophy type 1 had more frequent and severe white matter lesions than controls in total white matter lesions scores assessing the whole brain (sum of bihemispheric scores/total score, P = 0.03).

MRI confirmed the severe white matter lesions concentrated around the periventricular, pons, external capsule and the anterior temporal pole and multiple subcortical lacunar infarcts (Figure 1D-1F).

The MR images were inspected by 2 to 3 well-trained radiologists, and images with the following findings were excluded from this study: head injuries, brain tumors, hemorrhages, major and lacunar infarctions, and moderate to severe white matter hyperintensities.

Recent neuropathologic reports of severe white matter damage (i.e. leukoencephalopathy) in patients with HIV-1 infection and on HAART with very low viral load [10], [11], [12], [13], suggest that additional patterns of primary brain disease are emerging, possibly due to as yet unexplained interactions between the virus, vulnerable populations of neural cells, and HAART [14], [15].

We observed nine rare non-synonymous SNPs, which were only present in subjects with severe white matter lesions.

More severe gray matter deficits have been reported in alcohol relapsers than those who maintained abstinence (Pfefferbaum et al. 1998).

At this stage, severe white matter disorganization is the rule, with marked losses of myelin and axons, accompanied by severe vessel wall and perivascular space abnormalities [ 11].

Except for two of these SNPs (V1183M and V1952M), they were exclusively or mainly detected in subjects with severe white matter lesions.

MRI was not exploited for the diagnosis of FTD but was used to rule out other major neuropathologies such as tumors, stroke, severe white matter disease, or inflammation.