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However, there are severe limitations with these models that inhibit their use.
Hardware-based first stages usually win out where power consumption, dynamic range, and speed are the issue, but have severe limitations with regard to flexibility.
The results also showed that the soils of the study site are marginally suitable for the production of maize (Zea mays L .. Low limitations with respect to exchangeable bases (Ca, Mg, K and Na) and severe limitations with respect to B (< 0.15 mg kg− 1), pH (< 6.20), P (< 6.5 mg kg− 1 soil) and clay content (> 63%) were detected.
However, in comparison with our study, the sample size of 174 participants was even smaller, which poses severe limitations with regard to the statistical power of the analysis.
A total of 493/1012 (49%) participants scored less than 4 on both the Rivermead mobility index and Barthel index scales, suggesting that approximately half of the sampled population had both severe limitations on functional activity when engaging in personal activities of daily living, and severe limitations with mobility.
In addition, Lawrence et al [ 31] presents concerns over the severe limitations with regard to estimating prevalence of specific conditions (using self-report data) due to the fact that individuals frequently do not know and therefore cannot identify the specific musculoskeletal disease that affects them.
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In this paper, we tackle this severe limitation with the definition of an air mirror, which solves the low reflectivity problems: with the appropriate design, the working wavelength matches with the condition of total internal reflection (TIR) only at the air mirror and is reflected back to the hollow prism.
However, these aspects also highlight some severe limitation with current GPCR screening formats.
Tensile testing has been shown to permit direct intrinsic determinations of tissue quality, but it was recognised by Black et al. [27] that this method of testing was associated with severe limitations, particularly with difficulties between bone clamp interfaces.
On the other hand, regarding the floating point data management, TinyOS provides a software emulation with severe limitations when using with matrix data.
Carr and Bowman have severe limitations (Carr struggles with positioning and timing on an island; Bowman struggles with hip swivel).
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