"severe limitations of" is correct and usable in written English.
You can use it to refer to something that is severely hampered or restricted in some way. For example: "The project was fraught with severe limitations of time, money, and resources."
Recognizing the severe limitations of agricultural systems based on one or a limited number of crops, for both subsistence and export, the Conference emphasized the need for increased attention to crop diversification and the integration of crop and animal husbandry in balanced systems of land utilization.
The news media are operating perhaps under the most severe limitations of any recent conflict.
That in itself should point up the severe limitations of world-weariness as a guiding philosophy.
Mr. Mangrum figured, even with severe limitations of space, why not do something similar at the medical center?
After a visit to Manus Island in October 2013, UNHCR again raised concerns about the "severe limitations" of finding safe, long term solutions for non-Melanesian refugees.
The volume of data that can be quickly passed in and out of homes keeps running up against the severe limitations of traditional twisted copper telephone lines.
However, a severe limitation of this approach is the lack of insights into the mode of action of compounds selected during the primary screen.
The most severe limitation of the ACIP is its sensitivity to operator performance, which can lead to a pile of poor integrity or inconsistent quality.
To overcome a severe limitation of data, this study employed a multiple-pattern load-parameter estimation (MPLE) method that couples the numerical model with a Genetic Algorithm (GA) and a cluster algorithm to construct an uncertainty-based decision support system.
Chronic migraineurs often develop medication overuse headaches with severe limitation of their quality of life.
Expanding existing streets is often not an option due to already intense development and the severe limitation of available land.
