A more severe issue in terms of (research) ethics is that of the missing "informed consent" in SMA, comprehensively dealt with in Krieger, Grubmüller et al. [36].
On the other hand, interference is a severe issue in multi-AP based scheme due to the simultaneous transmission from multiple APs to EUs, which often makes the resource allocation problem non-convex and thus hard to solve [5].
Lastly, sequence-nonspecific detection chemistries like SYBR Green give signal from all dsDNA products generated, including primer dimers and nonspecific amplification products, which can be a severe issue in complex samples.
However, when we checked the standard errors of these two variables in the logistic model, they were 0.01 for waist circumference and 0.02 for BMI, indicating that there was no substantial inflation, and suggesting that multicollinearity, if any, was not a severe issue in this model.
I'm incredibly reluctant to prescribe an antidepressant for someone under the age of 18, as more severe issues should not be managed in primary care, but with the obstacles in place and when presented with extreme distress, it can sometimes feel like the only option to help in the interim.
The same year, a report from academics at the Australian Catholic University found that there were severe workforce issues in Australian children and families social work, with some jurisdictions having turnover rates as high as 30 to 40%.
Because what he's about to spend on cake could go towards tackling the water sanitation crisis, which has claimed more than 4,000 lives in Harare in the last five years… Severe sanitation issues in Zimbabwe's capital city mean that residents continue to be exposed to a high risk of waterborne diseases, including cholera, Human Rights Watch confirmed in a report in November 2013.
Groundwater, clean and safe in ancient days in contrast to present decades, shows how quick industrialization creates severe environmental issues in most countries (Santhosh and Revathi 2014).
They donated books and other items to a village in West Africa (Anzu Global), funded non-profits that conduct operations for patients with severe health issues in Africa (Hermes Traducciones) allocated funds toward building a bridge in a remote area of Nepal (SDL Foundation), and translating for rural communities (Translationary).
Gynecological morbidity is among the most severe health issues in the developing world [ 1, 2].
