On the skin it has a severe irritant effect.
His accounts troubled many readers and proved a severe irritant to the White House.
FINALES are like allergies: they come at the same time every year, and for some they are a severe irritant.
While we were in the EU, Europe was prepared to try and make it work, even though we were a severe irritant.
FOR several months a blogger going by the name of Minerva, the Roman goddess of wisdom, has proved a severe irritant to South Korea's government.
The dominant morphology is that of a severe irritant chemotherapy effect with significant architectural disarray and dysmaturation of the epidermis with a number of bizarre keratinocytes present within the epidermis typical for chemotherapy effect.
Ending a decade of negotiations on the placement of American troops within Japan, the agreement seeks to remove a severe irritant in relations by reducing American military personnel on Okinawa, where residents complain of noise and crime.
The effects of mild and severe irritant concentrations of NaOH (2% and 8%, respectively) on corneal opacity, swelling and epithelial integrity were studied, and the inflammatory status assessed using F4/80 and MPO as macrophages and neutrophils markers, respectively.
Patients with plaque psoriasis applying the 0.1% gel formulation for 20 minutes, followed by washing with water, developed much less frequent and severe irritant contact dermatitis than traditional treatment with the same formulation.
"If you get a positive result in either of these assays, you can use that as a positive for the purposes of classifying and labeling [a material] as a severe irritant," says Marilyn Wind, chair of ICCVAM and a deputy associate executive director with the Consumer Product Safety Commission.
