In the athetoid type, the incidence of severe intellectual disability is much lower, and occurrence of convulsive seizures is rare.
Hypothyroidism in infants, though treatable, can occasionally lead to severe intellectual disability and growth retardation leading to dwarfism.
The incidence of severe intellectual disability in PDD-NOS patients is low relative to other pervasive developmental disorders.
His situation was complex, as is often the case for people who fall into the gray space between severe intellectual disability and borderline development delay.
The manifestations of this deletion, in addition to the "cat cry" that gives the syndrome its name, include severe intellectual disability and an abnormally small head.
Rett syndrome, also called cerebroatrophic hyperammonemia, rare progressive neurological disorder characterized by severe intellectual disability, autism-like behaviour patterns, and impaired motor function.
The consequences of metabolic imbalance may be severe; intellectual disability, seizures, decreased muscle tone, organ failure, blindness, and deafness may occur, depending on which enzyme is dysfunctional.
Purine and pyrimidine disorders have a wide spectrum of signs and symptoms, including autism, kidney stones, susceptibility to infections, and severe intellectual disability.
A high fluid intake and the drug allopurinol are helpful in treating the joint and kidney problems, but have no effect on the severe intellectual disability.
Without prompt and aggressive treatment, most of these disorders have a poor prognosis, resulting in severe intellectual disability and other forms of illness.
In mucopolysaccharidoses and mucolipidoses (both lysosomal disorders), fat and carbohydrates are deposited in the nervous system and in other tissues; severe intellectual disability, motor and ocular disorders, and skeletal abnormalities are common features.
