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Another protection mechanism initiated in the HL subjected cells is the severe induction of the H2O2 peroxidase gene PRX Q, encoding a protein similar to the A. thaliana peroxiredoxin Q that is suggested to be involved in protection of PSII [45].
In contrast, the aminocoumarins resulted in a severe induction of the recF-gyrB-gyrA operon.
However, the GNPs of 50 nm size produced more severe induction of proinflammatory cytokines as compared to smaller GNPs.
IL-1β is associated with a more severe induction of cell death compared to TNF-α and was also observed in the present study (data not shown).
EcEE has cytotoxic activity on HT29 cancer cells leading to mitotic disruption and non-apoptotic cell death without severe induction of DNA damage.
Furthermore, severe induction of apoptosis in primary human hepatocytes was reported by adenoviral gene transfer of TRAIL (Armeanu et al, 2003), which further restricts the use of this delivery method.
Similar(54)
For severe diabetes induction, STZ is administered at 40 50 mg/kg body weight intravenously or intraperitoneally during adulthood.
Considering that lin(bh23 ) animals show a similar but more severe VPC induction defect, we suspected that this could be another allele of Cbr-lin-39.
One pool of serum, obtained 2 hours after polymicrobial severe sepsis induction in mice, partially inhibited thioglycolate-induced neutrophil migration into the peritoneal cavity of naïve mice.
This study was concurrent chemoradiotherapy, and toxicities, such as mucositis, leukocytopenia and neutropenia, were thought to be more severe than induction chemotherapy, so that we reduced the initial dose level of docetaxel and 5-FU.
Animals submitted to mild and severe sepsis induction and treated with BOC-1 presented decreased neutrophil migration, larger bacterial loads in peritoneal exudate, and heightened lung damage when compared with untreated control animals.
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