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Mean conjunctival hyperaemia severity, evaluated on a 4-point scale (none to severe), increased +0.1 to +0.3 from baseline across treatment groups, with no treatment differences in the proportion of subjects with hyperaemia.
Mild tooth wear decreased with age whereas moderate and severe increased with age.
These observations are all consistent with severe, increased microvascular permeability in susceptible mice in response to S. aureus infection.
One AE in each group was considered severe: increased transaminases in the infliximab plus methotrexate group and renal colic in the methotrexate-alone group.
Over time, the proportion of trauma leading to hospitalization that was categorized as slight decreased (55% to 41%) while the proportion of trauma categorized as moderate or severe increased (42% to 50%).
(Informant 2, female, 20 years in family practice) Some of the family physicians' responses suggest that the fact that the patient cases reviewed were cancer-related, and thus often long-term and severe, increased the learning impact of the patient case reviews.
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The LCC planning officers concluded the Rosacre Wood plan would involve a "severe" increase in traffic, particularly HGVs, creating an "impact on existing road users, particularly vulnerable road users and overall highway safety".
Vitamin A deficiency damages immune systems so that illness is more common and more severe, increasing under-five death rates by up to a third.
14 All seven had a moderate-to-severe increased parkinsonism during follow-up, although 3/7 had no parkinsonism at baseline.
What's more, younger drivers who typically face a much higher cost of cover, will face a more severe increase.
When they overheat, the batteries showed "much more severe increases in temperature and pressure" than other battery types.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com