Sentence examples for severe implication on from inspiring English sources

The process is related to increasingly evident extreme conditions in the summer time, that strongly improve the energy demand for cooling with negative impacts on the energy balance as well as on thermal comfort conditions of the end users and of urban population with severe implication on health and wellbeing.

Histone 4 is the only nucleosomal subunit present as a single copy gene and thus its down-regulation could have severe implication on the nucleosomal assembly during the P. falciparum schizont stage.

Changes in the shape, mechanical characteristics or the integrity of the erythrocyte has severe implications on the functionality of the cell, as can be seen in several dysfunctional states of the erythrocyte, whether it is environmentally induced, due to hereditary defects or diseased states [ 3].

Even a restructuring would likely have severe implications on his 125-member staff.

This brings to severe implications on international competitiveness especially for energy-intensive industrial sectors.

"With Dropbox you can access your files through the browser and this is a feature which has very severe implications on how security has to be laid out.

The strength of a slope materials and groundwater depth (GWD) could have severe implications on the stability of the slope (Tables 11, 12, 13).

Without local capacity to continue assistance in the absence of the organization's local presence, the possibility for abrupt stoppage of assistance is great and may have severe implications on beneficiaries and future attempts at reinstating assistance.

However, termination of drug release from such a CRDDS at tdel and/or a declining drug input function towards the terminal phase of tdel from a first order kinetic CRDDS can have severe implications on plasma drug concentration and steady state fluctuations for a drug with very short half-life.

"It's something that has severe implications on privacy and First Amendment rights and there is no basis to believe it improves security at all".

In the mouse, it was shown that Dmrt2 is required for somite differentiation with severe implications on axial skeleton development [24].