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We explored the nature of the severe habituation defects in rpm-1 mutants further.
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Severe deficiency in the intersession habituation demonstrated by Bmal1-/ and Clock/Clock mice both in locomotion and rearing suggests that Bmal1-/ and Clock/Clock mice lack memory of the previous day experience and allows speculating that transcription activity of the BMAL1 CLOCK complex is necessary for the LTM formation, which requires de novo synthesis of both RNA and protein [ 31].
Webb and colleagues reported group differences in 18- to 30-month-olds with more severe ASD symptoms during a habituation protocol (longer peak look and more time required to habituate) that were present for social and nonsocial stimuli but markedly stronger for social stimuli (Webb et al., 2010).
Toddlers with more severe symptoms of autism showed slower habituation to faces than comparison groups; slower face learning correlated with poorer social skills and lower verbal ability.
These authors reported that the effects of PBDE congeners 99 or 153 on habituation were significantly more severe in mice that were ≥ 6 months of age compared with younger animals (Viberg et al. 2003a; 2003a).
For the autism spectrum group, lower levels of habituation of the amygdala to the face stimuli were associated with more severe social impairment.These results suggest amygdala hyperarousal in autism spectrum disorders in response to socially relevant stimuli.
Behavioral strategies that address habituation may be useful adjuncts to educational approaches in restoring hypoglycemia awareness and protection against severe hypoglycemia.
Habituation explains a lot.
It's called habituation.
This is called habituation.
This was more than habituation.
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