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The study includes patients from two hospitals, but, as expected, the number of patients in moderate and severe groups was significantly lower than in mild group.
The median number of platelet transfusions in the mild, moderate, severe and very severe groups was 0, 1, 1 and 3, respectively.
Similar(58)
Severe groups were animals whose lesions covered more than half of the body surface.
Patients in mild and severe groups were ill at similar ages.
The moderate and severe groups were significantly larger than controls (p<0.001 for both, Figure 3b).
For the baseline covariate, the moderate and severe groups were combined (MMSE <20) since there were relatively few patients classified as severe at baseline.
In the present study, the NEI VFQ-25 composite scores in the mild, moderate and severe groups were 76.1±12.8, 69.5±14.1 and 64.6±17.2, respectively.
Scores for non-symptomatic, mild, moderate and severe groups were expected to differ significantly from one another when compared using the Analysis of Variance (ANOVA) test.
Mean overall life impact scores for mild, moderate and severe groups were 73.04, 63.68 and 49.26, respectively, in TREAT RLS 1, and 74.93, 67.44, and 50.54, respectively, in TREAT RLS 2. These results indicate the 'known groups' or discriminative validity of the RLSQoL.
These results require confirmation as radiographic disease severity is only weakly associated with quadriceps muscle strength [ 8, 9] and the severity of symptoms in the severe group was not specified.
Severe group was more likely to have hematemesis as presenting symptoms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com