Sentence examples for severe genes from inspiring English sources

As drought stress became more severe, genes with products involved in energy metabolism, osmotic balance, changes in cell structure, and leaf senescence and abscission showed altered expression in leaves.

We conclude that the TI-2 antigen-induced altered selection of TD Ag-inducible clones and its severe gene-specific influence on further somatic mutations and affinity maturation represents a network memory, which we hypothesize to be mediated by anti-idiotypic regulatory T cells.

These may involve less or more severe gene expression changes toward a mesenchymal cell phenotype.

Patients with severe gene mutations or deletions may express little or no protein.

In line with a more severe gene suppression in T1 35S:HvCesA8 lines, these plants died early but those in T1 35survived4 survived to maturity.

Alternatively, some might be ancient intra-specific duplicates, but their paralog-ship was no longer traceable because of severe gene divergence or erosion of duplication signatures.

All the multiple Arabidopsis regions that match to similar regions in Prunus share none or less than three sequences, suggesting Arabidopsis genome underwent severe gene loss after multiple genome duplication.

Thus, the severe gene loss we described in obligate intracellular genomes comparing to free-living bacteria, may represent an irreversible evolutionary trajectory that constrains existence outside a eukaryotic cell, and limits transitions in lifestyles (e.g. parasitic versus mutualistic associations with hosts) [ 7, 47].

Therefore, we decided to first focus on the transitional patterns that can be identified from a "normally aging" to an "AD-severe" gene expression profile in hippocampus.

Importantly, the reduction of Tip60 binding upon Hdac6 KD was most severe at genes whose expression is regulated by Tip60-p400, compared to genes not regulated by the complex.

We make three observations: 1) The depression in average MAF around coding regions is more severe for genes that are most highly conserved across species and decreases as genes become less conserved, a pattern that is repeated at conserved sites in non-coding regions.