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In the present study, 'Severe Actinic Damage' was defined as an anatomical area with >5 lesions, dominated by grade II-III AKs with moderate to severe field cancerization.
This finding would not be as significant if the subjects with more severe field loss were also widely distributed in terms of the SFI.
A summary of the results from the different HRQoL instruments is shown in Table 2.> -wrap-foot> a26 incomplete questionnaires, b22 incomplete questionnaires, c36 incomplete questionnaires, dOne missing value, eSevere actinic damage defined as patients with multiple lesions, dominated by grade II-III AKs with moderate to severe field cancerization.
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Our study showed severe visual field abnormalities in VKH patients before treatment as evidenced by severely decreased MD value and P value.
Most patients are subjectively asymptomatic, but visual acuity, preceded by severe visual field defects, is severely impaired in a small number of patients [ 1].
In a subsequent study in patients with visual impairment or moderate to severe visual field loss, only 39% were able to instill a single drop without touching the eye; age (<70 vs ≥70 years) was found to be a significant predictor for less successful instillation [ 4].
This issue is likely to be more severe in field sites where less information is available on which to provide independent estimate of the rates of aboveground biomass accumulation, e.g. [18].
This is because the fatigue cracks under non-proportional loading are subjected to more severe strain field than those under proportional loading, even though the crack size and applied strain are the same.
In essence, the laminate behaved as a smart structure, being resistant to failure under normal conditions, but allowing full loss of constraint in the severe stress strain field ahead of a loaded crack.
These areas correspond to severe visual field narrowing and deterioration of the electroretinographic (ERG) response.
According to Nelson's glaucoma staging system, patients were stratified as mild, moderate, and severe visual field loss (VFL).
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