The depression ratings varied from mild (entry of 20 39) to moderate-severe (entry of 0 19), and the mania ratings varied from hypomania (entry of 61 80) to moderate-severe (entry of 81 100).
A negative β co-efficient indicates that more severe study entry scores were associated with milder symptoms at week 16.
At each stress level, i.e., moderate and severe, those entries with non-significant differences between means of the non-stress and the respective stress level are the drought-resistant genotypes.
Planned subgroup analyses 13 were based on severity of the woman's pre-eclampsia at trial entry (severe, moderate or mild), whether randomised before or after delivery and perinatal mortality (PNM) in the country (high, medium or low).
Planned subgroup analyses 17 were based on the following: severity of the mother's pre-eclampsia at trial entry (severe, moderate, mild), gestation at birth (≤33 completed weeks, >33 completed weeks), perinatal mortality (PNM) in the country (high, medium or low) 27 and whether the mother received maintenance therapy of trial treatment by the intramuscular or the intravenous route.
Second, the level of membrane damage was severe, allowing the entry of 3 kDa and 40 kDa FITC-dextrans, but the membrane was not completely broken down, as evidenced by the preservation of the ability to exclude 500 kDa and 2000 kDa FITC-dextran molecules and the maintenance of the cell boundary.
Monotherapy patients had more severe disease at entry, reflecting the fact that this population consisted primarily of TNFi-IR patients.
The mean volume of new WMH was also decreased significantly with active treatment compared with placebo, the difference being greatest for patients with severe WMH at entry.
Prolongation of PT was found in more than 90% of the patients with severe sepsis at entry to this large trial.
We observed a severe deficiency in entry of strain L99 in HeLa and Caco-2 cells as well as poor cell-to-cell transmission with macrophages and L929 fibroblasts when compared to 1/2a EGD-e (data not shown).
Children are often institutionalized as a result of maltreatment or parental inability to provide care for them; thus, it is expected that many institutionalized children have been exposed to multiple severe stressors before entry into care.
