Sentence examples for severe drawbacks in from inspiring English sources

However, they suffer from severe drawbacks in terms of their membrane penetration mechanisms that mainly include endocytosis and pore formation.

However, it also means the actual alleles fixed under the artificial selection regime may have severe drawbacks in natural conditions.

When lasers were first invented, laser speckle was considered to be a severe drawback in using lasers to illuminate objects, particularly in holographic imaging because of the grainy image produced.

There are several drawbacks in LDA.

Nevertheless, there are several drawbacks in using biomass fuels.

Both approaches have severe drawbacks, as in the first approach potentially useful information is discarded while in the latter approach similarities across cell stages are not considered.

Analysis of EBM according to these themes leads to the conclusion that EBM can be a useful tool, but has severe drawbacks when used in isolation in the practice of individual patient care.

It should be noted that well-known WSN algorithms as (Elson et al.2002; Palchaudhuri et al.2003; Römer2001; Ping2003) exhibit severe drawbacks when they run in mesh network topologies, because they do not offer some of the aforementioned features.

But these amine-based solutions suffer severe drawbacks such as high energy consumption in regeneration process, high corrosive rate of equipment, essential pretreatment steps, large absorber volume and high sorbent cost.

In our study, these techniques were found to be equally safe and effective in the treatment of BPH without any severe drawbacks as long as patients were selected according to risk factors.

In fact, they often perform well under a specific constraint but have severe drawbacks under others.