Sentence examples for severe drawback in from inspiring English sources

When lasers were first invented, laser speckle was considered to be a severe drawback in using lasers to illuminate objects, particularly in holographic imaging because of the grainy image produced.

However, they suffer from severe drawbacks in terms of their membrane penetration mechanisms that mainly include endocytosis and pore formation.

However, it also means the actual alleles fixed under the artificial selection regime may have severe drawbacks in natural conditions.

Both approaches have severe drawbacks, as in the first approach potentially useful information is discarded while in the latter approach similarities across cell stages are not considered.

There are several drawbacks in LDA.

Nevertheless, there are several drawbacks in using biomass fuels.

Analysis of EBM according to these themes leads to the conclusion that EBM can be a useful tool, but has severe drawbacks when used in isolation in the practice of individual patient care.

On the other hand, the failure of the compactness theorem to generalize to L ω1,ω) in any useful fashion is a severe drawback as far as applications are concerned.

The occurrence of significant degradation by β-scission reaction is a severe drawback affecting the classical procedure of polypropylene (PP) functionalization in the melt with maleic anhydride (MAH) or derivatives and free radical initiators.

However, this leads to an even more severe drawback, unmet demand.

However, there is a severe drawback that pixels locating at the lower and central parts of an image are likely to be assigned with nearer depths, resulting in a smoothly tilted depth pattern for most input images.