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Second, while telomere dysfunction in late generations of telomerase knockout mice gives a severe deleterious impact on highly regenerative tissues (Lee et al., 1998), this study focused on the diseases associated with non-regenerative/post-mitotic tissues (i.e., heart and brain) and identified G-tail, the telomere-related parameter, as the predictive disease marker.
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The C-terminal mutation led to a severe decrease in the level of Ind1 protein, which had a deleterious impact on complex I activity, quantified as an 80% decrease in assembly and function.
The greater biological vulnerability and stronger natural selection in utero of male versus female fetuses during severe famine may result in a stronger selection effect among men than women, obscuring the deleterious impact of famine exposure on the risk of mental illness in men later in life.
"It had a deleterious impact".
Whatever the explanation, their water consumption has a deleterious impact.
A. This is a a huge issue, a major problem that has a profound and deleterious impact on the district.
Marriage laws barring same-sex couples from getting married in Australia have a "significant and deleterious" impact on their mental health, the peak body for psychiatrists has said.
At the same time, Mr. McGreevey said, the project "will not have a deleterious impact" on municipal services like schools or local roads.
A man might be tempted to conclude that unsupervised pharmacological experimentation may not, as was previously believed, have a deleterious impact on longevity.
To understand the administration's deleterious impact on this promising research, one has to recall the political landscape of the late 1990s.
Until relatively recently the deleterious impact of the trade gap has been largely offset by a positive balance of investment income from our assets overseas.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com