Sentence examples for severe deleterious effect from inspiring English sources

Clearly, this had a severe deleterious effect on recall.

Our results show that in vivo TRF2 abrogation in a highly proliferative tissue such as skin leads to the most severe deleterious effect as compared to TRF1, TPP1, and RAP1 loss (Martinez et al., 2009, 2010; Tejera et al., 2010).

Also small doses of very toxic substances can lead to severe deleterious effects.

The data presented here further suggests that the mutation does not have as severe deleterious effects on mtDNA replication as it has on recombination - resulting in almost complete abolishment of the otherwise abundant heart mtDNA recombination intermediates.

However, buffering severe acidosis by sodium bicarbonate is known to be associated with severe deleterious effects.

The NUPT integrations into functional genes or gene regulatory regions could cause severe deleterious effects.

As already discussed, the high ROS amounts produced by ETC impairment lead to severe deleterious effects in trypanosomatids.

Mutations in genes required for the proper functioning of the mitochondrial respiratory chain can therefore have severe deleterious effects.

Any substitution of these functionally involved residues generally leads towards the complete loss of biological functions and render severe deleterious effects compared to other polymorphisms of nonconserved site [ 13, 75].

Transposable elements (TEs) are present in all organisms, and their activity can both induce severe deleterious effects by disrupting gene activity and create genetic novelties possibly useful from an evolutionary point of view (Wicker et al. 2007).

Schizophrenia is a mental illness affecting 1% of the world population and has severe deleterious effects on quality of life; mainly because symptoms begin at an early age and full recovery has not been achieved with current therapies [ 1].