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M-CSF deficient mice showed osteopetrosis due to severe deficiency of osteoclasts and macrophages [7], [8].
In addition, patients also exhibit several biochemical traits including a typical albeit unusual combination of severe deficiency of the terminal component of the mitochondrial respiratory chain cytochrome c oxidase (COX) in muscle, brain, and colonic mucosa, leading to high levels of lactate in blood, and accumulation of ethylmalonic acid (EMA) and C4- and C5-acylcarnitines in fluids.
Blood tests revealed a severe deficiency of potassium, which plays an important role in muscle functioning.
The blood tests they ordered revealed that the patient had a severe deficiency of vitamin B6.
That George W. Bush failed to rush back to the White House from his vacation in Crawford, Tex., to demand to know what, in particular, was being done to prevent potential hijackers from boarding planes shows at least a severe deficiency of curiosity, if not sensitivity, perhaps both.
Herman Cain declared that the "pursuit of happiness is under attack" and repeated his popular line that the biggest crisis facing America is a "severe deficiency of leadership crisis in the White House".
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As a new growing season begins in the Iowa-Nebraska-Illinois breadbasket, severe deficiencies of soil moisture are creating a potential new threat to farmers' chronically sagging fortunes.
In addition, HPV has probably been acquired many years before severe deficiencies of immune functions in AIDS patients develop.
Severe deficiencies of iodine can result in mental retardation, while even mild deficiencies can restrict children's mental capacity and negatively affect their performance in school.
At present, prediction algorithms have to accept severe deficiencies of recall to ensure high specificity that is naturally considered to be more important.
Even in cases of severe deficiency, a daily dose of 100 mg (1 mg = 0.001 gram) for adults or 10 to 25 mg for infants and children, accompanied by a normal diet, commonly produces a cure within several days.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com