Sentence examples for severe defect of from inspiring English sources

These observations suggest that the acquisition of motor skill may remain relatively unaffected by lesions that give rise to a severe defect of general memory.

Limbal stem cell deficiency (LSCD) is a severe defect of the limbal stem cells leading to vision loss due to conjunctival epithelial invasion and neovascularization.

In vivo kinetics of bacterial dissemination revealed a severe defect of multiplication of the trkH mutant in the blood of infected animals.

Despite the severe defect of pro-B cells in Egr-2 cTg mice, the development of B cells in Egr-2 cKO mice is normal.

Taken together, these results confirm a severe defect of virulence and cytotoxicity correlated with the absence of the TolC protein in L. pneumophila.

In contrast, no significant Gag production was detected in cells transfected with the wild-type sequence, consistent with the severe defect of protein expression previously reported for non-optimzed sequence [8].

These severe defects of the central nervous system originate from a corrupted process of neurulation and are better known as neural tube defects (NTDs).

Targeted inactivation of cytosolic thioredoxin (Txn1) was associated with severe defects of inner cell mass proliferation and embryonic death at the blastocysts stage [3].

In humans, oral intake of RA during the first weeks of pregnancy engenders highly variable morphological and neural lesions collectively named "retinoic acid embryopathies" (RAEs); these include severe defects of the jaws and of the middle and external ear [4] [7].

Moreover, our previous studies suggest that exposure to more than 50 µM of metals often resulted in severe defects of locomotion behaviors; however, exposure to 2.5 µM of metals would induce moderate but significant decrease of locomotion behaviors (27).

Thus, it is not surprising that such a lack of two myosin II-isoforms would result in more severe defects of apical junctions comparing to selective knock-down of NMMIIA.