However, the metastability of modulated martensite imposes a severe constraint on the capacity of these alloys as promising materials for sensors and actuators.
However, the folding and modification requirements of complex proteins place a severe constraint on the type of protein that can be successfully displayed using this strategy, a restriction that could be resolved by similarly engineering a eukaryotic virus for display purposes.
Subsidence in Ripon, and many other places underlain by gypsum poses a severe constraint on the development of those areas.
Not only is there a substantial contribution by non-allometric SShD, which suggests that allometry is not a severe constraint on the evolution of SShD, but the allometries themselves seem to be variable.
Though the NONSTA process is the most general time-homogeneous Markov process, it is still simplistic and imposes a severe constraint on the evolution of base composition: if two leaf nodes are at the same distance from the root, then the process stipulates that the corresponding sequences must have the same composition.
The interdependency of parenchymal cells and their NPC companions places a severe constraint on zone-specific patterns of gene expression and, thus, on the inherent response to hepatotoxins in vivo.
Having the rate of situational awareness data update as fast as 1Hz, puts another severe constraint on the computational effectiveness of the path generation algorithm.
Local vision gives increased autonomous capability, but it requires substantial computing power that is difficult to provide given the severe constraints of small size and battery-powered operation.
Agriculture designed under the severe constraints of limited materials resources in space would make a positive contribution toward solving the food shortages and environmental problems facing humans on Earth, and may provide an effective sustainable solution for our civilization.
