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An alignment through environmentally protected areas seems to be a severe constraint for upgrading operations on the existing alignment.
I really enjoyed this experience and was fortunate to be able to write a Ph.D. proposal with my supervisor, to characterise a viral disease that was a severe constraint for rice production in West Africa.
The need for intravenous administration is a severe constraint for mass passive immunization and would likely limit this practice to a few recipients.
In contrast to the template binding pocket, there is a severe constraint for the incoming nucleotide for insertion of 8-oxodGTP.
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The upper political levels and external events pose severe constraints for the implementation of local transition initiatives.
On the other hand, courtship behavioural traits often involve morphological and behavioural adaptations in both sexes; this suggests that their evolution might be under severe constraints, for instance irreversibility of character loss.
Rather, it is the suspension of donor support that continues to place a severe constraint on the public resources available for financing road and sewerage investment.
The lack of numerous tsetse datasets for modeling is a severe constraint.
He sang the chorus to himself — "I paid the cost to be the boss" — and remarked that one price of leadership, for Obama, had been a severe constraint on the very wanderlust that Bourdain personifies.
One of the most severe constraint is that the SCFCL should operate safely for any faults, especially those with low prospective short-circuit currents.
However, the metastability of modulated martensite imposes a severe constraint on the capacity of these alloys as promising materials for sensors and actuators.
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