Sentence examples for severe clinical forms from inspiring English sources

Severe clinical forms with neurological [23], [24] and cardiac involvements [25], [26] have also been reported in the literature.

The role of IgG1 in both the development and as a prognostic marker of severe clinical forms after DENV infection has been clearly demonstrated before [60].

It was followed by a fast spread of DENV2 across the country [11], [12], becoming endemic in some areas [13] and causing severe clinical forms [14].

Dengue vaccine development has been hampered by concerns that cross-reactive immunological memory elicited by a candidate vaccine could increase the risk of development of more severe clinical forms.

More than half of the cases had severe clinical forms (pancolitis).

Furthermore, asymptomatic infections may progress to severe clinical forms in immunocompromised persons, for example, in AIDS patients (16 ).

The most severe clinical form, Walker Warburg syndrome (WWS), is characterized by congenital muscular dystrophy and severe neurological and ophthalmological defects.

Developmental delay, epilepsy and neonatal diabetes syndrome (DEND) represents the most severe clinical form of PNDM [ 4].

VL is the most severe clinical form within the leishmaniasis complex, which is endemic in 88 countries with an at-risk population of approximately 350 million (1).

However, approximately 30% of chronically infected individuals develop a severe clinical form in which digestive and/or cardiac alterations often lead to death [ 64– 64].

HPS case-patients who needed mechanical ventilation and hemodynamic support were considered to have a severe clinical form, while those that did not require such support were considered to have a moderate form.