Sentence examples for severe changes including from inspiring English sources

Rats treated with Bio-CuNPs via i/v route showed severe changes including cytoplasmic vacuolization of central vein surrounded hepatocytes and hepatic haemorrhage for 14th day observation (Fig. 6c).

Low dietary protein coupled with exposure to this metal induces more severe changes, including biochemical defects, structural disorders, and altered physiologic functions.

Radiographic findings are often poorly correlated to symptomatology; however, visualisation of severe changes, including large osteophyte formation, marked disc space narrowing, sclerosis of vertebral plates and posterior subluxation, are more often associated with pain and discomfort [ 52].

Mild changes constituted periprosthetic collections less than 5 cm in diameter, moderate comprised soft tissue masses of fluid collections greater than 5 cm in diameter, gluteal muscle atrophy or bone marrow edema and severe changes including extension through deep fascia, tendon avulsion, bone marrow replacement or fracture, or neurovascular involvement.

The most severe morphologic changes, including electron-dense mitochondrial inclusions, were found in the fetuses with delayed recovery of the fetal heart rate after the final occlusion.

Unexposed heart samples exhibited normal architecture (Fig. 3), whereas those from mice exposed to increasing TiO2 NP dose presented severe pathological changes, including infiltration of inflammatory cells, myocardial cells swelling, sparse cardiac muscle fibers, and disorder of muscle cell array (Fig. 3).

The fourth through the seventh cervical vertebrae had severe degenerative changes including ventral wedging, osteophytic lipping on the margins of the centra and on the superior and inferior articular surfaces, and vertebral ankylosis, or fusion of the cervical vertebrae (Figure 5a).

This particular patient also had severe joint changes, including ruptures of both menisci, osteoarthritis (score 3), cartilage damage (score 3) and generalized thickening of the joint capsule.

COPD is a disease characterized by airflow limitation caused by severe pathophysiological changes including chronic bronchitis, small airway remodelling, mucus production and the development of emphysaema [ 2].

The pathogenesis of COPD is characterized by severe pathophysiological changes including chronic bronchitis, small airway remodelling, mucus production and the development of emphysaema [ 2].

Sepsis induces severe cardiovascular changes including an increase in cardiac output, a decrease in peripheral resistance and a loss of intravascular fluids, which can lead to severe shock (Annane et al, 2005).