Sentence examples for severe by itself from inspiring English sources

Although this impairment in anterograde mitochondrial transport is not severe by itself, it could contribute to peripheral neuropathy over a sustained time period as observed with some POLG1 mutations [36], [37] and AZT treatment [58].

That's already a severe disease by itself.

The US Supreme Court has ruled on more than one occasion that the creation of a hostile environment requires a pattern of incidents - and no single incident, no matter how severe, can by itself be a pattern.

That's a pretty severe punishment all by itself.

During the first hours and days after ROSC, half of these patients will subsequently suffer from a postresuscitation disease, which can include a severe shock leading by itself to death.

The first minister dismissed attacks from the Scottish Labour leader Johann Lamont by saying that Labour had inflicted severe damage on itself by aligning itself with Osborne.

Although norovirus gastroenteritis is commonly regarded as a mild, short-lasting intestinal disorder which resolves by itself, severe dehydration and subsequent hospitalization are common complications in very young and very old persons, especially in those immunocompromised and with underlying diseases.

Of course, it could be the case that the effect of the neurotoxic prefrontal lesion was due to multiple penetrations of the frontal cortex with a needle rather than any specific action of the neurotoxin itself; furthermore, these data, by themselves, do not exclude the possibility that unilateral inferotemporal ablation has a severe effect on scene learning by itself.

In the current study, no evidence of excessive muscle collagen deposition was found in wild-type grafted muscles compared with osteopontin-null grafted muscles, suggesting that in response to a single severe injury acute osteopontin overexpression by itself does not induce collagen deposition and fibrosis.

"These reductions are severe by any measure," he said.

It was constant and severe by then, but she was not to be deterred.