Sentence examples for severe bone erosion from inspiring English sources

We observed that control mice displayed severe bone erosion, pannus formation, and synovitis.

The disease pathology involves breakdown of joint cartilage, tendon and ligament stretch, and when severe, bone erosion [ 4].

Radiological analysis revealed severe bone erosion in the joints of CIA rats, as shown in Figure 3b.

Injection with Ad-IL-17 caused a mild inflammatory reaction in the joint on day 4, which increased to severe on day 7, when moderate to severe bone erosion and PG depletion were apparent (Fig.  3a e).

The degree of bone erosion in the ankle joint was scored as described previously [ 21] (0 = no swelling or bone damage, 1 = mild bone damage, 2 = moderate bone erosion, and 3 = severe bone erosion).

Severe bone erosion and joint damage were observed in PBS- or Fc-injected mice (arrows), but mild to moderate erosion (arrowheads) and periarticular osteopenia (asterisks) were observed in the mice injected with VEGF-Trap or Tie2-Fc.

Severe bone erosions and synovial inflammation in AIA revealed by x-ray (figure 6A C) and MRI (figure 6D F) were attenuated by NBQX treatment.

Briefly, infiltration of cells and cartilage damage were all scored separately from 0 (normal) to 3 (severe), and bone erosions were scored from 0 (normal) to 4 (severe); proteoglycan loss (safranin O, fast green stain) was scored from 0 (normal) to 3 (complete loss of staining).

A histological scoring system was used: 1, mild; 2, moderate; and 3, severe synovitis or bone erosion [ 24].

However, compared with the control mice, the CIA mice had significant changes in the cartilage and bone area, including severe cartilage and bone erosion and inflammatory cell infiltration.

The histologic evaluation (at day 35) of the paws from vehicle-treated mice revealed signs of severe arthritis, with bone erosion.