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Exact(8)
No severe bleeding event as defined in the protocol has been observed.
For the first three patients no intense toxicity, particularly no severe bleeding event, was observed within the required 4 weeks of treatment.
Severe bleeding event rates for patients receiving TA in the bevacizumab-treated groups were similar in frequency to the placebo groups, ranging from 0 to 8% or 0 to 67 events per 100 patient-years.
PTR during chemotherapy for AML significantly increased the risk of early and late deaths caused by a severe bleeding event.
The modified SOFA score did not include the platelet component ICU intensive care unit, SAPS II simplified acute physiology score II, SOFA sequential organ failure assessment score aThe nadir platelet count was the lowest platelet count recorded prior to the first severe bleeding event, or during the whole ICU stay for patients without severe bleeding.
Of the five patients receiving concurrent therapy and experiencing a severe bleeding event in the combined bevacizumab-containing groups, two were receiving heparin and three were receiving warfarin.
Similar(52)
Although IPA is well suited for defining the risk of minor complications, prediction of more severe bleeding events may be challenging.
These patients are at increased risk for severe bleeding events.
Thirty-eight patients reported 47 other severe adverse events, of which five were severe bleeding events.
Other studies have also reported that severe bleeding events and infections account for a large portion MDS-related deaths [ 22].
No severe bleeding events as defined in the protocol were observed under treatment with enoxaparin as well as in a corresponding follow-up of 30 days.
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