It is also important to note that the current patient population had severe baseline symptoms, including baseline erosions, despite only several months since RA onset.
The adjusted risk of systemic complications increased with age and was much higher in patients with more severe baseline gallstones, whereas no clear age or severity-related differences in risk emerged with regard to surgical-related 30-day complications, once other cofactors were taken into account.
Changes from baseline to week 24 in the nine SIB domain scores were analyzed in the intent-to-treat (ITT) population (baseline MMSE 0 to 20), in patients with more severe baseline AD (MMSE 0 to 16), and in severity strata based on baseline MMSE scores (0 to 5, 6 to 10, 11 to 15, 16 to 20).
Based on these results, the difference in AD conversion ratio might be dependent on the severity of pre-dementia AD, reflecting that MCI patients with severe baseline memory deficits rapidly converted to AD.
Exclusion criteria: ASA > III, severe baseline hemodynamic impairment which required invasive monitoring and amine infusion.
Severe baseline pain was reported in 366 of the 794 subjects.
The percentage of patients being pain free two hours after start of treatment decreased substantially depending on pain intensity at baseline (88.5%, 66.1% and 42.4% of patients with mild, moderate or severe baseline pain).
And elsewhere, they report "True drug benefits were nonexistent to negligible among depressed patients with mild, moderate and even severe baseline symptoms, whereas they were large for patients with very severe symptoms".
We speculate that changes caused by ETS in severe asthmatics may be less evident because those patients start from a more severe baseline.
Patients with more severe baseline CHD had better adherence.
Treatment differences were more marked in those with more severe baseline symptoms (P<0.001).
