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Patients had to have been diagnosed using the standard criteria [6] 6. Psychiatric comorbidities of the following types: severe Axis I (affective disorder), or any Axis II (personality disorder) = 1 point.
Embryos with progressively lower quantities of T exhibit more severe axis truncations (Stott et al., 1993).
No patients were rejected because of severe Axis I or Axis II psychiatric disorder.
Exclusion criteria included the following: (1) diagnosis with a severe Axis I psychiatric disorder (dementia, schizophrenia, paranoid disorder, or abuse of alcohol and/or drugs) or a severe Axis II disorder (personality disorder) that, from the clinician's point of view, might prevent them from following the study protocol; and (2) refusal to participate.
Those excluded will be patients with severe Axis I psychiatric disorders (dementia, schizophrenia, paranoid disorder, alcohol and/or drug use disorders), severe Axis II disorders or somatic disorders which, from the clinician's point of view, prevent patients from carrying out a psychological assessment.
Exclusion criteria included the following: (1) diagnosis of a severe Axis I psychiatric disorder (dementia, schizophrenia, paranoid disorder, or abuse of alcohol and/or drugs) or a severe Axis II disorder that, from the clinician's point of view, might prevent them from following the study protocol; and (2) refusal to participate.
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Although taz −/− RPE appears normal, the inclusion of one mutant taz allele within a yap −/− background (yap −/−; taz +/−) enhanced the loss of RPE and led to more severe body axis, heart and NR defects compared with yap −/− siblings (Fig. 1J-J″).
For this study, severe DSM-IV Axis I (affective disorders) or any Axis II (personality disorders) was considered important in refractoriness [7].
Close to the flame axis, severe light attenuation occurs.
"ATG phenotype" was defined as decreased anterior-posterior axis, severe notochord kinks and pericardial edema.
An issue of major concern in the design of long wavelength systems is optical aberration or distortion, which can be particularly severe in off-axis systems.
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