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Moreover, in SOD1 and Neurotomized mice our results suggest LC3, Fn14, Bcl3 and Gadd45a as candidate genes involved in the maintenance of the severe atrophic state.
Very severe atrophic submandibular gland was also found (bottom).
Also, very severe atrophic submandibular gland was found (Fig. 1 bottom).
In light of the histological outcomes and implant failures, special attention must be placed to prevent soft tissue dehiscence when CCXBB is used in severe atrophic alveolar crests.
We hypothesized that this characteristic may help in the differential diagnosis with serpiginous choroiditis, since cases of serpiginous choroiditis may lead to severe atrophic legacy not only in the retina but also in the choroid.
Within the limitations of this clinical study, we may conclude that the use of CCXBB in combination with DBBM particles and a native bilayer collagen membrane for staged lateral bone augmentation in severe atrophic alveolar crests achieved significant horizontal crestal width allowing for staged implant placement in most of the patients.
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31 Nevertheless, in 2014, Bellafill® (previously named Artefill®) has got FDA approval "for moderate-to-severe, atrophic, distensible facial acne scars on the cheek in patients over 21 years of age".
Alternatively, the atrophy in these regions may already have been too severe to show further correlations with performance: the group comparison confirmed that the insula and amygdala were severely atrophic in progressive supranuclear palsy, both in grey and surrounding white matter.
In fair-skinned persons the skin appears severely atrophic with multiple teleangiectasis and a variety of premalignant lesions such as actinic keratosis, whereas in dark-skinned persons deep furrows and severe solar elastosis occur.
The hippocampus and amygdala were severely atrophic.
As demonstrated by Capellá et al., R399Q in XRCC1 showed an association with an increased risk of severe chronic atrophic gastritis [ 20].
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