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Nearly every disease can be considered severe (associated with infant or child mortality), significant (associated with progressive disease and reduced life span), or requiring significant intervention or treatment.
Each variant should also be given a phenotypic score, which in most cases will be 'classic or most severe' associated with homozygous or hemizygous loss-of-function variants or with well-characterized missense variants (e.g., sickle cell), but many variants are associated with milder phenotypes which must be explained when known.
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Patients had severe DAD associated with severe NB and alveolar hemorrhage.
We enrolled all the patients admitted in ICU for more 48 hours with surgical severe sepsis associated with severe deficiency of coagulation natural inhibitors.
Q: What about the severe complications associated with the 1976 swine flu vaccine?
At a recent therapy session, he met with a tall, courtly man in his seventies, who suffers from severe depression associated with Parkinson's disease.
"Western European countries are also reporting severe cases associated with H1N1," said Dr Caroline Brown, programme manager for influenza at the WHO in Europe.
This patient population with severe disability associated with migraine, tolerated lasmiditan treatment.
We describe a patient with severe multineuropathy associated with Waldenström's macroglobulinaemia.
The use of PP in patients with severe ARDS associated with brain injury is at high risk of intracranial hypertension.
Nitroglycerin is indicated in severe hypertension associated with volume overload and pulmonary edema.
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